MCID: PMC5394630 DOI: 10.1186/s40413-017-0145-4
Since mite allergens are the most relevant inducers of allergic diseases worldwide, resulting in significant morbidity and increased burden on health services, the International Collaboration in Asthma, Allergy and Immunology (iCAALL), formed by the American Academy of Allergy, Asthma and Immunology (AAAAI), the American College of Allergy, Asthma and Immunology (ACAAI), the European Academy of Allergy and Clinical Immunology (EAACI), and the World Allergy Organization (WAO), has proposed to issue an International Consensus (ICON) on the clinical consequences of mite hypersensitivity. The objectives of this document are to highlight aspects of mite biology that are clinically relevant, to update the current knowledge on mite allergens, routes of sensitization, the genetics of IgE responses to mites, the epidemiologic aspects of mite hypersensitivity, the clinical pictures induced by mites, the diagnosis, specific immunotherapeutic approaches, and prevention.
World Allergy Organ J
Hypersensitivity; Mites; Consensus
Sánchez-Borges, Mario; Fernandez-Caldas, Enrique; Thomas, Wayne R.; Chapman, Martin D.; Lee, Bee Wah; Caraballo, Luis; Acevedo, Nathalie; Chew, Fook Tim; Ansotegui, Ignacio J.; Behrooz, Leili; Phipatanakul, Wanda; Gerth van Wijk, Roy; Pascal, Demoly; Rosario, Nelson; Ebisawa, Motohiro; Geller, Mario; Quirce, Santiago; Vrtala, Susanne; Valenta, Rudolf; Ollert, Markus; Canonica, Giorgio Walter; Calderón, Moises A.; Barnes, Charles S.; Custovic, Adnan; Benjaponpitak, Suwat; and Capriles-Hulett, Arnaldo, "International consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem." (2017). Manuscripts, Articles, Book Chapters and Other Papers. 1077.
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