Immunohistochemical Staining of Pediatric Solitary Angiokeratomas.
The precise etiology and subtype of vessels constituting angiokeratomas is poorly understood. We sought to characterize the vessels by studying prospero-related homeobox gene-1 and D2-40 expression in 22 pediatric solitary angiokeratomas. Routine histologic examination demonstrated a mix of lymph-containing vessels and erythrocyte-filled small vessels. Our results suggest that angiokeratomas may in part be comprised of vessels with lymphatic differentiation.
Adolescent; Angiokeratoma; Child; Child, Preschool; Female; Humans; Infant; Male; Retrospective Studies; Skin Neoplasms
Prindaville, B., Lawrence, H., Singh, V., Nopper, A. J., Horii, K. A. Immunohistochemical Staining of Pediatric Solitary Angiokeratomas. Pediatric dermatology 34, 211-213 (2017).