Immunohistochemical Staining of Pediatric Solitary Angiokeratomas.

Creator(s)

Brea Prindaville, Children's Mercy Hospital
Hillary Lawrence
Vivekanand Singh, Children's Mercy Hospital
Amy J. Nopper, Children's Mercy HospitalFollow
Kimberly A. Horii, Children's Mercy HospitalFollow

Document Type

Article

Publication Date

3-1-2017

Identifier

DOI: 10.1111/pde.13089

Abstract

The precise etiology and subtype of vessels constituting angiokeratomas is poorly understood. We sought to characterize the vessels by studying prospero-related homeobox gene-1 and D2-40 expression in 22 pediatric solitary angiokeratomas. Routine histologic examination demonstrated a mix of lymph-containing vessels and erythrocyte-filled small vessels. Our results suggest that angiokeratomas may in part be comprised of vessels with lymphatic differentiation.

Journal Title

Pediatric dermatology

Volume

34

Issue

2

First Page

211

Last Page

213

MeSH Keywords

Adolescent; Angiokeratoma; Child; Child, Preschool; Female; Humans; Infant; Male; Retrospective Studies; Skin Neoplasms

Recommended Citation

Prindaville B, Lawrence H, Singh V, Nopper AJ, Horii KA. Immunohistochemical Staining of Pediatric Solitary Angiokeratomas. Pediatr Dermatol. 2017;34(2):211-213. doi:10.1111/pde.13089