Title

Clinical Outcomes among Diagnostic Subgroups of Infants with Severe Bronchopulmonary Dysplasia through 2 Years of Age.

Document Type

Article

Publication Date

12-1-2018

Identifier

DOI: 10.1055/s-0038-1655761

Abstract

OBJECTIVE: This article aimed to identify readmission risk factors through 2 years of life for infants with severe bronchopulmonary dysplasia (BPD) who do not require tracheostomy and ventilatory support after neonatal intensive care unit (NICU) discharge. It also aimed to identify if clinical differences exist between the subcategories of severe BPD.

STUDY DESIGN: A retrospective chart review was performed on 182 infants with severe BPD born between 2010 and 2015. A total of 130 infants met the inclusion criteria and were stratified into three groups based on their respiratory status at 36 weeks of gestational age: group A-oxygen (O2), group B-assisted ventilation (AV), group C-both O2 and AV. NICU clinical risk factors for readmission were assessed at set time points (6/12/18/24 months). Reasons for readmission were assessed for the entire cohort and severe BPD subgroups.

CONCLUSION: An NICU diagnosis of neurologic abnormality, necrotizing enterocolitis, invasive NICU infection, dysphagia, and O2 at NICU discharge differed between the three subgroups of severe BPD. The most common cause of readmission was viral respiratory tract infection. Inhaled steroid use remained stable over time, while oxygen use and diuretic use declined over time. Risk factors for readmission in the entire cohort included g-tube, O2 use, and diuretic use at 12 months. There was no significant difference in readmission rates between the three BPD subgroups.

Journal Title

American journal of perinatology

Volume

35

Issue

14

First Page

1376

Last Page

1387

MeSH Keywords

Bronchopulmonary Dysplasia; Child, Preschool; Databases, Factual; Female; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Logistic Models; Male; Missouri; Oxygen; Patient Discharge; Patient Readmission; Positive-Pressure Respiration; Respiratory Tract Infections; Retrospective Studies; Risk Factors

Keywords

BPD; Babies

Collection

Neonatology

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