Variability of surgical prophylaxis in penicillin-allergic children.

Creator(s)

David F. Butler, Children's Mercy Hospital
Brian R. Lee, Children's Mercy HospitalFollow
Sarah Suppes, Children's Mercy Hospital
Tracy Sandritter, Children's Mercy Hospital
Jason G. Newland
Lory Harte, Children's Mercy Hospital
Jennifer Goldman, Children's Mercy Kansas CityFollow

Document Type

Article

Publication Date

12-1-2018

Identifier

DOI: 10.1017/ice.2018.244

Abstract

We retrospectively evaluated the effect of penicillin adverse drug reaction (ADR) labeling on surgical antibiotic prophylaxis. Cefazolin was administered in 86% of penicillin ADR-negative (-) and 28% penicillin ADR-positive (+) cases. Broad-spectrum antibiotic use was more common in ADR(+) cases and was more commonly associated with perioperative adverse drug events.

Journal Title

Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America

Volume

39

Issue

12

First Page

1480

Last Page

1483

MeSH Keywords

Adolescent; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefazolin; Child; Child, Preschool; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Electronic Health Records; Female; General Surgery; Humans; Male; Pediatrics; Penicillins; Preoperative Care; Retrospective Studies; Washington

Recommended Citation

Butler DF, Lee BR, Suppes S, et al. Variability of surgical prophylaxis in penicillin-allergic children. Infect Control Hosp Epidemiol. 2018;39(12):1480-1483. doi:10.1017/ice.2018.244