Title

Second Reported Case of Pediatric Bladder Alveolar Soft Part Sarcoma as Secondary Malignancy After Prior Cytotoxic Chemotherapy.

Document Type

Article

Publication Date

8-2019

Identifier

DOI: 10.1016/j.urology.2019.04.002

Abstract

Alveolar soft part sarcoma (ASPS) is a rare malignancy with high rates of metastasis at presentation, defined by an unclear cellular origin and a unique unbalanced ASPSCR1-TFE3 translocation (der(17)t(X:17)(p11:q25)).1 ASPS is insensitive to chemotherapy and has been reported to involve the bladder only twice in the pediatric literature; once as a primary malignancy,2 and once as a secondary malignancy after cytotoxic chemotherapy.3 Herein, we report the third case of pediatric bladder ASPS in a female patient who received cytotoxic chemotherapy for low-risk neuroblastoma. This would represent the second case of pediatric bladder ASPS as a secondary malignancy after prior chemotherapy.

Journal Title

Urology

Volume

130

First Page

148

Last Page

150

MeSH Keywords

Antineoplastic Agents; Female; Humans; Male; Neoplasms, Second Primary; Neuroblastoma; Sarcoma, Alveolar Soft Part; Urinary Bladder Neoplasms

Keywords

Antineoplastic Agents; Neoplasms, Second Primary; Neuroblastoma; Sarcoma, Alveolar Soft Part; Urinary Bladder Neoplasms

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