A longitudinal case series description of meningitis due to Streptococcus gallolyticus subsp. pasteurianus in infants

Creator(s)

J. Michael Klatte, Children's Mercy Hospital
Jill E. Clarridge, VA Medical Center
Denise Bratcher, Children's Mercy HospitalFollow
Rangaraj Selvarangan, Children's Mercy HospitalFollow

Document Type

Article

Publication Date

1-2012

Identifier

DOI: 10.1128/JCM.05635-11; PMCID: PMC3256716

Abstract

Streptococcus gallolyticus subsp. pasteurianus, previously known as Streptococcus bovis biotype II.2, is known to cause multiple infectious complications, including bacterial meningitis, in adults. Only sporadic individual case reports have identified this pathogen as a cause of meningitis in infants. This study is the first to longitudinally document S. gallolyticus subsp. pasteurianus as a cause of meningitis in four epidemiologically unrelated infants less than 2 weeks of age. The 16S rRNA gene sequences of all 4 isolates were identical, and further were identical to 3 central nervous system (CNS) strains (two adults and one child) reported in existing literature. S. gallolyticus subsp. pasteurianus is an increasingly recognized cause of meningitis and bacteremia in the newborn period, and it merits further study with respect to etiology of infection. Copyright © 2012, American Society for Microbiology. All Rights Reserved.

Journal Title

Journal of Clinical Microbiology

Volume

50

Issue

1

First Page

57

Last Page

60

Recommended Citation

Klatte, J., Clarridge, J. E., Bratcher, D., Selvarangan, R. A longitudinal case series description of meningitis due to Streptococcus gallolyticus subsp. pasteurianus in infants Journal of Clinical Microbiology 50, 57-60 (2012).