Title

The Human Parechoviruses: An Overview

Document Type

Article

Publication Date

2011

Identifier

DOI: 10.1016/j.yapd.2011.03.008

Abstract

In the summer of 1956, the first two members of the Parechovirus genus were isolated from Ohio children with diarrhea. Human parechoviruses (HPeVs) types 1 and 2, as they would eventually become known, were originally designated as the 22nd and 23rd members (Harris and Williamson strains, respectively) of the “enteric cytopathic human orphan (ECHO) group” or echoviruses (E22 and E23, respectively). Over the next 50 years, the advent of molecular and genomic virology would provide tools for their in-depth characterization and the identification of other members of the Parechovirus genus. This article reviews past and current medical literature concerning the virology, epidemiology, clinical significance, and diagnosis of the HPeV.

Journal Title

Advances in Pediatrics

Volume

58

Issue

1

First Page

65

Last Page

85

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