DOI: 10.1016/j.ebr.2020.100376; PMCID: PMC7393451
Polyspike ictal-onset absence seizure has been reported in adult patients with genetic generalized epilepsy but is a novel pattern in the pediatric population. Absence seizures are usually associated with generalized spike-and-wave on EEG. However, we present the case of a 10-year-old girl with Down syndrome and developmental delays who presented with atypical absence seizure associated with an unusual electroencephalographic (EEG) pattern of polyspike ictal-onset. Recognition of this ictal pattern in the pediatric population, as previously reported in adult populations, is important as it can have therapeutic and prognostic implications.
Epilepsy Behav Rep
Absence seizure; Down syndrome; Ictal pattern; Polyspike ictal-onset
Abdelmoity S, Ilyas M. Polyspike ictal-onset absence seizures in a pediatric patient with Down syndrome. Epilepsy Behav Rep. 2020;14:100376. Published 2020 Jul 2. doi:10.1016/j.ebr.2020.100376