Primary Spinal Epidural/Extramedullary Ewing Sarcoma in Young Female Patients.
Document Type
Article
Publication Date
11-27-2019
Identifier
DOI: 10.5435/JAAOSGlobal-D-19-00072; PMCID: PMC6903810
Abstract
Primary spinal epidural/extramedullary ewing sarcoma (ES) is a rare extraosseous lesion. Extraosseous ES has a similar demographic as osseous ES, primarily affecting adolescents and young adults and male propensity. Reported 5-year survival is 0% to 37.5% for spinal extraosseous ES.
Methods: Two girls, 19 and 14 months old, presented with progressive lower extremity paraplegia and incontinence. Both had a compressive epidural/extramedullary mass without metastases and underwent decompression with multilevel laminectomy and tumor excision. Primary spinal epidural/extramedullary ES was diagnosed.
Results: Case 1 received 34 weeks of chemotherapy and radiation therapy, and case 2 received 14 cycles of chemotherapy and autologous stem cell rescue without radiation therapy. After more than 5- and 8-year follow-up, case 1 and case 2 are walking and disease-free, respectively.
Conclusion: These cases are the youngest presentation reported for primary spinal epidural/extramedullary ES and suggest that toddlers have a better prognosis for survival than older children and adolescents.
Journal Title
J Am Acad Orthop Surg Glob Res Rev
Volume
3
Issue
11
PubMed ID
31875190
Recommended Citation
Fletcher AN, Marasigan JAM, Hiatt SV, Anderson JT, Taboada EM, Schwend RM. Primary Spinal Epidural/Extramedullary Ewing Sarcoma in Young Female Patients. J Am Acad Orthop Surg Glob Res Rev. 2019;3(11):e10.5435. Published 2019 Nov 27. doi:10.5435/JAAOSGlobal-D-19-00072
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