Title

PharmVar GeneFocus: CYP2C19.

Document Type

Article

Publication Date

2-2021

Identifier

DOI: 10.1002/cpt.1973

Abstract

The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele nomenclature for the polymorphic human CYP2C19 gene. CYP2C19 genetic variation impacts the metabolism of many drugs and has been associated with both efficacy and safety issues for several commonly prescribed medications. This GeneFocus provides a comprehensive overview and summary of CYP2C19 and describes how haplotype information catalogued by PharmVar is utilized by the Pharmacogenomics Knowledgebase and the Clinical Pharmacogenetics Implementation Consortium (CPIC).

Journal Title

Clinical pharmacology and therapeutics

Volume

109

Issue

2

First Page

352

Last Page

366

Library Record

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