Comparative risk of cardiac catheterisations performed on low birth weight neonates.

Document Type

Article

Publication Date

10-2013

Identifier

DOI: 10.1017/S1047951112002247

Abstract

To determine whether cardiac catheterisation procedures for low birth weight neonatesr < or = 2.5 kg carries a greater risk of complications compared with neonates > 2.5 kg, we conducted a single-centre retrospective case–control study. From 01/03 to 01/09, 46 consecutive neonates < 2.5 kg at the time of cardiac catheterisation were identified. For each low birth weight case, three control patients > or = 2.5 kg were randomly selected from our heart centre database during the same time period. Data included demographic characteristics, type of intervention, fluoroscopy time, contrast volume, pre- and post-blood urea nitrogen to creatinine ratio, physician performing procedure, procedural risk category, and all major and minor complications. The overall incidence of complications was higher in neonates < or = 2.5 kg compared with neonates > 2.5 kg (34.8% versus 17.6%, p = 50.023) because of a greater proportion of minor complications (34.8% versus 16.9%, p = 50.021). When specific minor complications were stratified, there was a greater incidence of hypotension requiring intravenous fluids in neonates < or = 2.5 kg (6.5% versus 0%, p50.015). After controlling for physician performing procedure and risk category, neonates < or = 2.5 kg remained at a higher risk for any complication (adjusted odds ratio = 3.2, 95% confidence interval 1.4–7.2, p = 0.005). The percentage of neonates having at least one major complication was not higher in the < or = 2.5-kg group (2.2% versus 2.2%). No procedural deaths occurred in either group.

Journal Title

Cardiology in the young

Volume

23

Issue

5

First Page

722

Last Page

726

MeSH Keywords

Atrial Septum; Balloon Valvuloplasty; Blood Urea Nitrogen; Cardiac Catheterization; Case-Control Studies; Contrast Media; Creatinine; Female; Fluid Therapy; Fluoroscopy; Humans; Hypotension; Infant, Low Birth Weight; Infant, Newborn; Logistic Models; Male; Multivariate Analysis; Odds Ratio; Operative Time; Postoperative Complications; Retrospective Studies; Risk Factors; Time Factors

Keywords

Atrial Septum; Balloon Valvuloplasty; Blood Urea Nitrogen; Cardiac Catheterization; Case-Control Studies; Contrast Media; Creatinine; Female; Fluid Therapy; Fluoroscopy; Humans; Hypotension; Infant, Low Birth Weight; Infant, Newborn; Logistic Models; Male; Multivariate Analysis; Odds Ratio; Operative Time; Postoperative Complications; Retrospective Studies; Risk Factors; Time Factors

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