Using the RETeval Device in Healthy Children to Establish Normative Electroretinogram Values.
PURPOSE: To provide normative data of full-field electro-retinogram (ERG) responses in the pediatric population using the RETeval ERG device (LKC Technologies, Inc) in healthy children without evidence of retinal disease.
METHODS: This was a single-site cross-sectional study of healthy pediatric patients with normal dilated fundus examinations and no known retinal diseases. Participants were recruited to undergo dilated full-field ERG using the handheld RETeval device. The International Society for Clinical Electrophysiology of Vision 5-step protocol was used. Photopic and dark-adapted scotopic responses were recorded using skin electrodes.
RESULTS: Main outcome measures were normative RETeval ERG values and correlation of age with measured ERG parameters. Thirty-eight eyes of 20 healthy patients (aged 4 to 17 years) were included in the study. Of the 20 normal patients, 9 were male and 11 were female. Normative mean, median, and range values were recorded for the measured full-field ERG parameters. Pearson correlation was moderately positive between age and oscillatory potential and scotopic dim flash amplitude (r = 0.59, P = .006 for both). A positive correlation was also found between age and cone a-wave implicit time (r = 0.67, P = .001).
CONCLUSIONS: The handheld RETeval system is a useful tool for obtaining full-field ERGs in children without anesthesia. Moderate positive correlations were observed between age and oscillatory potential and scotopic dim flash amplitude. A strong correlation was found between age and cone a-wave implicit time. The current study provides a baseline of normative full-field ERG values in children. [J Pediatr Ophthalmol Strabismus. 2021;58(1):17-22.].
Journal of pediatric ophthalmology and strabismus
Soekamto, C. D., Gupta, R., Keck, K. M. Using the RETeval Device in Healthy Children to Establish Normative Electroretinogram Values. Journal of pediatric ophthalmology and strabismus 58, 17-22 (2021).