Title

Preexisting Thyroid Disease in Pregnancy: A Brief Overview.

Document Type

Article

Publication Date

7-2022

Identifier

PMCID: PMC9462902

Abstract

Maternal thyroid disease, with both an excess or deficiency of thyroid hormone, raises the risk profile of affected pregnancies with regards to preeclampsia, preterm birth, placental problems, thyroid derangement of the fetus and neonate, and neurodevelopment of exposed fetuses later in life. Fortunately, close and tight management of thyroid disease within the fluctuating physiologic milieu of pregnancy offers opportunities to significantly improve perinatal outcomes. However, despite guidelines offered by American College of Obstetrics and Gynecology (ACOG) and American Thyroid Association (ATA), controversy persists regarding interpretation of thyroid labs, screening for disease, surveillance, fetal and placental thyroid physiology, and optimal medication and management strategies. This is a brief overview of what is known and unknown regarding thyroid disease and its impact on maternal, fetal, and pregnancy health.

Journal Title

Missouri medicine

Volume

119

Issue

4

First Page

360

Last Page

365

MeSH Keywords

Female; Humans; Infant, Newborn; Placenta; Pregnancy; Pregnancy Complications; Premature Birth; Thyroid Diseases; Thyroid Hormones; United States

Keywords

Placenta; Pregnancy; Pregnancy Complications; Premature Birth; Thyroid Diseases; Thyroid Hormones; United States

Library Record

Share

COinS