CKD Management Post-AKI: The Role of Biomarkers

Creator(s)

Heather A. Morgans, Children's Mercy HospitalFollow
Bradley A. Warady, Children's Mercy HospitalFollow

Document Type

Book Chapter

Publication Date

2-2021

Identifier

DOI: 10.1007/978-981-33-4554-6_17

Abstract

A biomarker is a measurable clinical parameter which can be used for early detection of a disease, to establish a definitive diagnosis, characterize the severity of a disease, or monitor the response to treatment interventions. The ideal biomarker is one that fulfills multiple purposes in one test and is easily obtained, cost effective, accurate, and generalizable to the entire population. A number of biomarkers have been identified in the setting of acute kidney injury (AKI), with their predictive capacity identified in adult and pediatric studies respectively. The potential application of these same biomarkers in the progression of chronic kidney disease (CKD) is currently under active investigation.

Journal Title

Advances in Critical Care Pediatric Nephrology

First Page

167

Last Page

176

Recommended Citation

Morgans, H.A., Warady, B.A. (2021). CKD Management Post-AKI: The Role of Biomarkers. In: Sethi, S.K., Raina, R., McCulloch, M., Bunchman, T.E. (eds) Advances in Critical Care Pediatric Nephrology. Springer, Singapore. https://doi.org/10.1007/978-981-33-4554-6_17