Splenic function post radiation therapy in childhood cancer survivors

Creator(s)

Joy M. Fulbright, Children's Mercy Kansas CityFollow
Kyla Alsman, Children's Mercy Kansas CityFollow
Ashley K. Sherman, Children's Mercy HospitalFollow
Kris Laurence, Children's Mercy HospitalFollow
Becky Lowry

Document Type

Article

Publication Date

7-2025

Identifier

DOI: 10.1016/j.ctro.2025.100961

Abstract

Study evaluated splenic function in childhood cancer survivors (CCS) who had received radiation to the spleen utilizing pRBC PIT (vesiculated erythrocytes) count compared to a non-radiated control group. Those exposed to < 20 Gy of radiation had PIT counts not significantly different from the control group. There was trend for higher pRBC PIT count in those exposed to higher doses of radiation.

Journal Title

Clinical and Translational Radiation Oncology

Volume

53

Keywords

Childhood cancer survivor; Splenic function; PIT count; Radiation; Infection

Comments

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Publisher's Link: https://www.ctro.science/article/S2405-6308(25)00051-5/fulltext

Recommended Citation

Fulbright J, Alsman K, Sherman AK, Laurence K, Lowry B. Splenic function post radiation therapy in childhood cancer survivors. Clinical and Translational Radiation Oncology. 2025;53:100961. doi:10.1016/j.ctro.2025.100961