Left ventricular dysfunction is associated with intraventricular dyssynchrony by 3-dimensional echocardiography in children.

Document Type

Article

Publication Date

3-1-2008

Identifier

DOI: 10.1016/j.echo.2007.08.046

Abstract

INTRODUCTION: We used 3-dimensional (3D) echocardiography to identify and quantify left ventricular (LV) dyssynchrony in children with LV dysfunction compared with control subjects.

METHODS: The 3D echocardiography LV full volumes were acquired in 18 children, 9 with LV dysfunction and 9 control subjects. The LV was subdivided into 16 segments (apex excluded). Time from end diastole to the minimal systolic volume for each segment was expressed as a percent of the R-R interval. The SD of these times provided a 16-segment dyssynchrony index (16-SDI). The second index (12-SDI) was similarly calculated using 6 basal and 6 mid segments. The third index consisted of 6 basal segments (6-SDI).

RESULTS: The dysfunction group exhibited significantly increased 16-SDI (P = .008) and 12-SDI (P = .01). The 16-SDI was negatively correlated with 3D ejection fraction and 2-dimensional fractional shortening.

CONCLUSIONS: Children with LV dysfunction demonstrate increased intraventricular LV dyssynchrony by 3D echocardiography, in a pattern that is negatively correlated with LV systolic function.

Journal Title

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

Volume

21

Issue

3

First Page

230

Last Page

233

MeSH Keywords

Child; Child, Preschool; Echocardiography, Three-Dimensional; Humans; Image Interpretation, Computer-Assisted; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic; Ventricular Dysfunction, Left; Ventricular Fibrillation

Keywords

3D ECG

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