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With the goal of developing a clinician-driven tacrolimus (TAC) pharmacokinetic dosing tool, our initial objectives were 1) to examine whether published TAC population pharmacokinetic (popPK) models could serve as a foundation for the dosing tool, and 2) evaluate their performance predicting TAC concentrations in an independent cohort of Children's Mercy patients.
Tacrolimus/pharmacokinetics; Tacrolimus/administration & dosage; Kidney Transplantation; Child; Adolescent; Infant
Population pharmacokinetics; Renal Transplantation
Medical Pharmacology | Pediatrics | Pharmaceutical Preparations
Chapron, Alenka and Abdel-Rahman, Susan M., "Predictive Performance of Existing Population Pharmacokinetic Models of Tacrolimus in Pediatric Kidney Transplant Recipients" (2019). Posters. 107.