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Mentor, Preceptor, Principle Investigator
Mentor: Dwight Yin MD, MPH
We present the case of a child with dedicator of cytokinesis 8 (DOCK8) deficiency and chronic, resistant HSV-1 mucocutaneous infections to illustrate the clinical utility of viral whole genome sequencing to detect active and latent HSV resistance mutations.
DOCK8 protein, human; Herpesvirus 1, Human; Drug Resistance, Viral; Whole Genome Sequencing; Child; Adolescent
DOCK8 Deficiency; HSV-1
Infectious Disease | Medical Genetics | Pediatrics | Skin and Connective Tissue Diseases | Virus Diseases
Stout, Sean; Greninger, A. L.; Selvarangan, Rangaraj; Freeman, A. F.; Newell, Brandon D.; Stahl, Erin; and Yin, Dwight, "Viral Whole Genome Sequencing for Antiviral Resistance in a Child with DOCK8 Deficiency and Recurrent HSV-1" (2019). Posters. 111.