Presenter Status
Fellow
Abstract Type
Research
Primary Mentor
Ryan Fischer, MD
Start Date
15-5-2025 11:30 AM
End Date
15-5-2025 1:30 PM
Presentation Type
Poster Presentation
Description
We created a model to test the immunosuppressive capacity of Helios+FOXP3+ eTregs compared to nTregs against islet-specific autoreactive T cells. We also showed that nTregs decrease the response of these cytotoxic T cells when co-cultured with BetaLox5 cells.
Included in
Endocrine System Diseases Commons, Higher Education and Teaching Commons, Immune System Diseases Commons, Laboratory and Basic Science Research Commons, Medical Education Commons, Pediatrics Commons, Science and Mathematics Education Commons
Engineering A Novel Treg Population to Control Autoimmune Diabetes
We created a model to test the immunosuppressive capacity of Helios+FOXP3+ eTregs compared to nTregs against islet-specific autoreactive T cells. We also showed that nTregs decrease the response of these cytotoxic T cells when co-cultured with BetaLox5 cells.
