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Publication Date



These guidelines do not establish a standard of care to be followed in every case. It is recognized that each case is different and those individuals involved in providing health care are expected to use their judgment in determining what is in the best interests of the patient based on the circumstances existing at the time. It is impossible to anticipate all possible situations that may exist and to prepare guidelines for each. Accordingly, these guidelines should guide care with the understanding that departures from them may be required at times.

Objective of the Guideline

To provide care standards for the infant or child presenting to the acute care setting for a first non-febrile seizure. The Seizure: First Non-Febrile Clinical Pathway renders guidance regarding recommended assessment and treatment to minimize variation of care.

Target Users

Physicians (Emergency Medicine, Urgent Care, Hospital Medicine, Fellows, Resident Physicians); Nurse Practitioners; Nurses; Pharmacy


Seizure; Nonfebrile; Afebrile




Clinical Pathways promote evidence based, safe, and high-value care for patients by providing clinical recommendations and standard processes. They are developed by multidisciplinary committees of subject matter experts, informed by methodical review of available evidence and consensus among committee members.

Clinical Pathways are updated on a revision schedule. Primary files will always be the most current update. Previous revisions are available upon request from Children’s Mercy Library Services.

Finalized June 2016; Revised February 2024

Seizures, First Nonfebrile Seizure

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Pediatrics Commons