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These guidelines do not establish a standard of care to be followed in every case. It is recognized that each case is different and those individuals involved in providing health care are expected to use their judgment in determining what is in the best interests of the patient based on the circumstances existing at the time. It is impossible to anticipate all possible situations that may exist and to prepare guidelines for each. Accordingly, these guidelines should guide care with the understanding that departures from them may be required at times.

Objective of the Guideline

To provide care standards for the patient diagnosed with Group A Streptococcus (GAS) pharyngitis. The Pharyngitis Clinical Pathway will standardize care and improve health outcomes in pediatric patients with GAS pharyngitis by establishing care focused on diagnosis, initiation of treatment and proper follow up as needed.

Target Users

Physicians (Residents, Fellows, Hospitalists, ED, UCC, Pediatricians); Nurses (Advanced Practice, Direct Care); Laboratory; Patients and Families

Clinical Questions Answered by Guideline

1. In pediatric patients diagnosed with group A streptococcal pharyngitis, is amoxicillin given QD as effective as amoxicillin or penicillin VK given BID?

2. In pediatric patients with group A streptococcal pharyngitis, is a 5–7-day course of antibiotics as effective as a 10-day course?


Pharyngitis; Streptococcal Pharyngitis; Antibiotics; Antibiotic Therapy




Clinical Practice Guidelines are updated on a revision schedule. Primary files will always be the most current update. Previous revisions are available upon request from Children’s Mercy Library Services.

Finalized/Revised: April 2018; April 2022; February 2024


Included in

Pediatrics Commons