Download Full Text (1.4 MB)

Download Sickle Cell Disease: Management of Acute Pain Algorithm (189 KB)

Download Sickle Cell Disease: Management of Mild Pain Algorithm (99 KB)

Download Intranasal Fentanyl Handout (132 KB)

Publication Date



These guidelines do not establish a standard of care to be followed in every case. It is recognized that each case is different and those individuals involved in providing health care are expected to use their judgment in determining what is in the best interests of the patient based on the circumstances existing at the time. It is impossible to anticipate all possible situations that may exist and to prepare guidelines for each. Accordingly, these guidelines should guide care with the understanding that departures from them may be required at times.

Objective of the Clinical Pathway

To provide care standards for patients diagnosed with sickle cell disease, who present to the emergency department for management of an acute pain episode. The Sickle Cell Disease: Management of Acute Pain Clinical Pathway provides guidance regarding recommended assessment and treatment to minimize variation of care and decrease the time to administration of first analgesic.

Target Users

Physicians (Emergency Department, Fellows, Resident Physicians); Nurse Practitioners; Nurses; Pharmacy



Sickle Cell Disease: Management of Acute Pain

Included in

Pediatrics Commons