A Pilot Study Evaluating the Impact of an Adherence-promoting Intervention Among Nonadherent Youth With Inflammatory Bowel Disease.

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DOI: 10.1016/j.pedn.2017.03.006


Purpose: This study examined the feasibility and impact of a multicomponent adherence intervention among youth with Inflammatory Bowel Disease (IBD) who presented to clinic with poor adherence.

Design and methods: Medical providers referred twelve adolescents for the intervention, who participated in 4 weekly visits with a caregiver aimed at improving adherence.

Results: Intervention session attendance was 100% and the intervention was rated as feasible and acceptable. Mean adherence increased 12% from baseline to post-intervention (p<0.01), and 6% from baseline to 1-month follow-up (p<0.025). A generalized linear model revealed significantly greater adherence from baseline to post-intervention (p<0.001), and from baseline to 1-month follow-up (p<0.01). Logistic Regression revealed a nearly 2:1 odds ratio during post-intervention when compared to the Baseline period (p<0.001).

Conclusions: Findings suggest that the delivery of a multicompoment adherence intervention to poorly adherent youth with IBD can result in significant improvements in their adherence to oral medication.

Practice implications: An intervention individually tailored to each family's unique adherence barriers is a feasible and promising treatment approach for improving medication adherence among nonadherent youth seen in clinical care.

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Journal of pediatric nursing



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MeSH Keywords

Adolescent; Adolescent Behavior; Attitude to Health; Female; Humans; Inflammatory Bowel Diseases; Male; Medication Adherence; Patient Compliance; Patient Education as Topic; Pilot Projects; Professional-Patient Relations; Quality of Life


Adolescents; Inflammatory bowel disease; Intervention; Self-management; IBS

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