Coadministration of mefloquine and chloroqine: use of a pharmacokinetic-based approach to reduce toxicity.

Creator(s)

J A. Lowry
A Corry
Laura Fitzmaurice, Children's Mercy HospitalFollow
Mary Anne Jackson, Children's Mercy HospitalFollow
G L. Kearns

Document Type

Article

Publication Date

2-1-2001

Identifier

DOI: 10.1097/00006454-200102000-00023

Abstract

A child with malaria from a chloroquine-resistant area received an accidental overdose of chloroquine administered by a parent. Application of pharmacokinetics permitted definitive treatment with mefloquine in a safe and effective manner.

Journal Title

The Pediatric infectious disease journal

Volume

20

Issue

2

First Page

223

Last Page

224

MeSH Keywords

Antimalarials; Child; Chloroquine; Drug Overdose; Drug Synergism; Drug Therapy, Combination; Humans; Malaria; Male; Mefloquine

Comments

Grant support

• 3 U01 HD31313-07S1/HD/NICHD NIH HHS/United States

Recommended Citation

Lowry, J. A., Corry, A., Fitzmaurice, L., Jackson, M., Kearns, G. L. Coadministration of mefloquine and chloroqine: use of a pharmacokinetic-based approach to reduce toxicity. The Pediatric infectious disease journal 20, 223-224 (2001).