Antibiotic Prophylaxis for Pyloromyotomy in Children: An Opportunity for Better Stewardship.
INTRODUCTION: Surgical site infection is very uncommon after pyloromyotomy in children, and it is considered a "clean" procedure under the traditional wound classification system. This study aims to investigate prophylactic antibiotic administration for pyloromyotomy among children's hospitals in the USA.
METHODS: The Pediatric Health Information System (PHIS) database was retrospectively reviewed from 2014 to 2015 including all patients less than 1 year old who had a principal diagnosis of pyloric stenosis and underwent pyloromyotomy. Patient demographics, hospital length of stay, and perioperative antibiotic administration were extracted.
RESULTS: A total of 4206 patients met study criteria. Most patients were male (84%) and Caucasian (70%). The median age at admission was 32 days (IQR 24-44 days), and median length of stay was 2 days (IQR 1-2 days). Antibiotics were administered perioperatively in 2153 (51%) patients with marked variation among children's hospitals. Antibiotics were given to more than 10% of patients in more than 90% of hospitals, and only two of 49 hospitals gave no antibiotic prophylaxis.
CONCLUSIONS: This study has shown that at several tertiary-level children's hospitals in the USA, antibiotic prophylaxis is administered for pyloromyotomy, a "clean" procedure. This highlights the need for standardization of care and more effective antibiotic stewardship in pediatric surgery.
World journal of surgery
Antibiotic Prophylaxis; Female; Health Information Systems; Humans; Infant; Infant, Newborn; Male; Pyloromyotomy; Retrospective Studies; Antimicrobial Stewardship
Williams, Kibileri; Lautz, Timothy; Hendrickson, Richard J.; and Oyetunji, Tolulope A., "Antibiotic Prophylaxis for Pyloromyotomy in Children: An Opportunity for Better Stewardship." (2018). Manuscripts, Articles, Book Chapters and Other Papers. 1366.