A Multicenter Cohort Analysis of Post-Endoscopy Complications in Children Undergoing Elective Outpatient Diagnostic Procedures.

Document Type


Publication Date



DOI: 10.1111/jgh.14318


BACKGROUND: Increased access to endoscopic procedures have entrenched these investigative tools in routine pediatric gastroenterology practice. Patient outcomes following endoscopy therefore are topical in the decision toward endoscopy. We studied the likelihood and patient characteristics of children admitted following ambulatory endoscopy.

METHODS: Hospitalization data was obtained from the Pediatric Hospital Information System including 49 tertiary children's hospitals in the US. Children who underwent ambulatory diagnostic endoscopy between 10/1/2005 and 9/25/2015 were included. The primary outcomes were post-procedure events resulting in unplanned admission (not for IBD management) or emergency room visit within 5 days. Unadjusted, univariate analyses were followed by multivariable analysis of the associations between patient characteristics and outcome using the R statistical package, v. 3.2.3.

RESULTS: During the study period, 217,817 patients underwent diagnostic endoscopy; 101 (0.05%) patients were admitted directly; 1314 (0.60%) were admitted to the same facility's ED with either a respiratory or gastrointestinal complication as a primary diagnosis within 5 days. None of the procedures resulted in death, female patients were more likely to experience adverse outcomes (p

CONCLUSIONS: Ambulatory pediatric endoscopy is safe; significant adverse outcomes are rare but more likely in female, non-white or Hispanic patients and in patients with significant chronic comorbidities.

Journal Title

Journal of gastroenterology and hepatology

MeSH Keywords

Endoscopy, Gastrointestinal/Complications; Multicenter Study; Child; Treatment Outcome; Ambulatory Care


Endoscopy, colon; small intestine (including capsule); upper GI; Hospital Information Systems; abdominal pain; child; complications; gastrointestinal hemorrhage; hospitalization; outcomes