DOI: 10.3201/eid2503.180960; PMCID: PMC6390745
© 2019, Centers for Disease Control and Prevention (CDC). All rights reserved. We evaluated enterovirus D68 seroprevalence in Kansas City, Missouri, USA, from samples obtained during 2012-2013. Neutralizing antibodies against Fermon and the dominant 2014 Missouri isolate were universally detected. Titers increased with age. Widespread circulation of enterovirus D68 occurred before the 2014 outbreak. Research is needed to determine a surrogate of protection.
Emerging Infectious Diseases
14-18949; 14-18952; 14-18953; EV-D68; Fermon; Hispanic; Kansas City; Missouri; United States; adults; age; children; enterovirus; microneutralization; neutralizing antibody; outbreak; race/ethnicity; respiratory infections; seroprevalence; viruses
Harrison CJ, Weldon WC, Pahud BA, Jackson MA, Oberste MS, Selvarangan R. Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA1. Emerg Infect Dis. 2019;25(3):585-588. doi:10.3201/eid2503.180960