The Hispanic Community Health Study/Study of Latinos Community and Surrounding Areas Study: sample, design, and procedures.

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DOI: 10.1016/j.annepidem.2018.11.002; PMCID: PMC6415666


PURPOSE: We describe the sample, design, and procedures for the Community and Surrounding Areas Study (CASAS), an ancillary to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). The aim of SOL CASAS was to test an ecological model of macro- and micro-neighborhood environment factors, intermediate behavioral (physical activity) and psychosocial (e.g., depression and stress) mechanisms, and changes in cardiometabolic health in Hispanics/Latinos.

METHODS: Between 2015 and 2017, approximately 6 years after the HCHS/SOL baseline (2008-2011), 1776 San Diego HCHS/SOL participants enrolled in SOL CASAS and completed a repeat physical activity assessment. Participants' residential addresses were geoprocessed, and macroenvironmental features of the home were derived from publicly available data concurrent with the HCHS/SOL baseline and Visit 2 (2014-2017). Microscale environmental attributes were coded for 943 unique routes for 1684 participants, with a validated observational tool, concurrent with Visit 2, for SOL CASAS participants only.

RESULTS: Of 2520 HCHS/SOL participants approached, 70.5% enrolled (mean age 55.3 years; 94% Mexican; 67.5% female). Accelerometer adherence (three or more days with at least 10 hours wear time) was outstanding (94%).

CONCLUSIONS: With its more comprehensive ecological model and well-characterized Hispanic/Latino population, SOL CASAS will advance the science concerning the contribution of neighborhood factors to cardiometabolic health.

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Annals of epidemiology



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MeSH Keywords

Adult; Aged; Cardiovascular Diseases; Cohort Studies; Community-Based Participatory Research; Depression; Environment; Exercise; Female; Hispanic Americans; Humans; Male; Middle Aged; Prospective Studies; Public Health; Research Design; Residence Characteristics; Risk Factors; Social Class; Social Environment; United States


Cardiovascular; Depression; Environment; Hispanic; Latino; Neighborhood; Physical activity; Risk factors

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