Document Type

Article

Publication Date

3-1-2016

Identifier

PMCID: PMC4918702 DOI: 10.1055/s-0035-1557108

Abstract

Inherited renal disease is a leading cause of morbidity and mortality in pediatric nephrology. High throughput advancements in genomics have led to greater understanding of the biologic underpinnings of these diseases. However, the underlying genetic changes explain only part of the molecular biology that contributes to disease manifestation and progression. Other omics technologies will provide a more complete picture of these cellular processes. This review discusses these omics technologies in the context of pediatric renal disease.

Journal Title

J Pediatr Genet

Volume

5

Issue

1

First Page

2

Last Page

14

MeSH Keywords

Kidney Diseases; Genetic Testing; Genomics; Epigenomics; Metabolomics; Infant; Child; Adolescent

Keywords

epigenomics; genomics; metabolomics; nephrology; next generation sequencing; proteomics; transcriptomics; Babies; Children; Teenagers

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