PMCID: PMC4918702 DOI: 10.1055/s-0035-1557108
Inherited renal disease is a leading cause of morbidity and mortality in pediatric nephrology. High throughput advancements in genomics have led to greater understanding of the biologic underpinnings of these diseases. However, the underlying genetic changes explain only part of the molecular biology that contributes to disease manifestation and progression. Other omics technologies will provide a more complete picture of these cellular processes. This review discusses these omics technologies in the context of pediatric renal disease.
J Pediatr Genet
Kidney Diseases; Genetic Testing; Genomics; Epigenomics; Metabolomics; Infant; Child; Adolescent
epigenomics; genomics; metabolomics; nephrology; next generation sequencing; proteomics; transcriptomics; Babies; Children; Teenagers
Willig, Laurel K., "Techniques and Approaches to Genetic Analyses in Nephrological Disorders." (2016). Manuscripts, Articles, Book Chapters and Other Papers. 311.