Squamous Carcinoma of the Cervix in a 15-Year-Old with Congenital HIV: A Case Report.
Document Type
Article
Publication Date
4-2021
Identifier
DOI: 10.1016/j.jpag.2020.08.014
Abstract
BACKGROUND: Human papillomavirus (HPV) is the most prevalent sexually transmitted infection (STI) worldwide. Immunocompetent hosts have intact defense mechanisms to prevent HPV infection, but immunocompromised patients are at higher risk for complications, including HPV-related cancers. Most of these cancers originate from high-risk HPV strains in sexually active patients.
CASE: Here we present a case of an immunocompromised adolescent who developed cervical cancer despite no prior sexual activity and only ever having had low-risk type HPV on biopsy.
SUMMARY AND CONCLUSIONS: To our knowledge, this is the first case report of a cervical cancer arising from a low-risk HPV strain in an immunocompromised, non-sexually active adolescent. This case highlights the importance of preventive and screening mechanisms in immunocompromised populations, as they are have a higher probability of HPV-related complications, even in the absence of traditional risk factors.
Journal Title
Journal of pediatric and adolescent gynecology
Volume
34
Issue
2
First Page
234
Last Page
237
Keywords
Adolescent; Case report; Cervical cancer; Condyloma; HPV; Immunocompromised
Recommended Citation
Evans M, Lawson A, Jarin JD, Wilson EE. Squamous Carcinoma of the Cervix in a 15-Year-Old with Congenital HIV: A Case Report. J Pediatr Adolesc Gynecol. 2021;34(2):234-237. doi:10.1016/j.jpag.2020.08.014
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