More Time in Glucose Range During Exercise Days than Sedentary Days in Adults Living with Type 1 Diabetes.

Creator(s)

Michael C. Riddell
Zoey Li
Roy W. Beck
Robin L. Gal
Peter G. Jacobs
Jessica R. Castle
Melanie B. Gillingham
Mark A. Clements, Children's Mercy HospitalFollow
Susana R. Patton
Eyal Dassau
Francis J. Doyle Iii
Corby K. Martin
Peter Calhoun
Michael R. Rickels

Document Type

Article

Publication Date

5-2021

Identifier

DOI: 10.1089/dia.2020.0495

Abstract

Objective: This study analysis was designed to examine the 24-h effects of exercise on glycemic control as measured by continuous glucose monitoring (CGM).

Methods: Individuals with type 1 diabetes (ages: 15-68 years; hemoglobin A1c: 7.5% ± 1.5% [mean ± standard deviation (SD)]) were randomly assigned to complete twice-weekly aerobic, high-intensity interval, or resistance-based exercise sessions in addition to their personal exercise sessions for a period of 4 weeks. Exercise was tracked with wearables and glucose concentrations assessed using CGM. An exercise day was defined as a 24-h period after the end of exercise, while a sedentary day was defined as any 24-h period with no recorded exercise ≥10 min long. Sedentary days start at least 24 h after the end of exercise.

Results: Mean glucose was lower (150 ± 45 vs. 166 ± 49 mg/dL, P = 0.01), % time in range [70-180 mg/dL] higher (62% ± 23% vs. 56% ± 25%, P = 0.03), % time >180 mg/dL lower (28% ± 23% vs. 37% ± 26%, P = 0.01), and % time /dL higher (9.3% ± 11.0% vs. 7.1% ± 9.1%, P = 0.04) on exercise days compared with sedentary days. Glucose variability and % time/dL did not differ significantly between exercise and sedentary days. No significant differences in glucose control by exercise type were observed.

Conclusion: Participants had lower 24-h mean glucose levels and a greater time in range on exercise days compared with sedentary days, with mode of exercise affecting glycemia similarly. In summary, this study offers data supporting frequency of exercise as a method of facilitating glucose control but does not suggest an effect for mode of exercise.

Journal Title

Diabetes technology & therapeutics

Volume

23

Issue

5

First Page

376

Last Page

383

Keywords

Continuous glucose monitoring; Exercise; Time in range; Type 1 diabetes; hyperglycemia; hypoglycemia; physical activity

Recommended Citation

Riddell MC, Li Z, Beck RW, et al. More Time in Glucose Range During Exercise Days than Sedentary Days in Adults Living with Type 1 Diabetes. Diabetes Technol Ther. 2021;23(5):376-383. doi:10.1089/dia.2020.0495