Variability in Ceftriaxone Dosing Across 32 US Acute Care Children's Hospitals.

Creator(s)

Rina A. Ferguson
Joshua C. Herigon
Brian R. Lee, Children's Mercy HospitalFollow
Mari M. Nakamura
Jason G. Newland

Document Type

Article

Publication Date

5-28-2021

Identifier

DOI: 10.1093/jpids/piab004

Abstract

Ceftriaxone is one of the most common antibiotics prescribed for hospitalized children in the United States. However, ceftriaxone is not dosed consistently. Sepsis/serious bacterial infection had high dosing variability. Dosing for central nervous system infection was frequently suboptimal. Future efforts should focus on optimizing and standardizing ceftriaxone dosing.

Journal Title

J Pediatric Infect Dis Soc

Volume

10

Issue

5

First Page

677

Last Page

681

Keywords

antibiotic dosing; ceftriaxone; inpatient antimicrobial stewardship; therapeutic dosing; weight-based dosing

Comments

Grant support

• T15 LM007092/LM/NLM NIH HHS/United States

Recommended Citation

Ferguson RA, Herigon JC, Lee BR, Nakamura MM, Newland JG. Variability in Ceftriaxone Dosing Across 32 US Acute Care Children's Hospitals. J Pediatric Infect Dis Soc. 2021;10(5):677-681. doi:10.1093/jpids/piab004