Document Type

Article

Publication Date

1-1-2016

Identifier

PMCID: PMC5056265 DOI: 10.1155/2016/5873208

Abstract

Abstract

Background. Approximately, one-third of patients with epilepsy are refractory to pharmacological treatment which mandates extensive medical care and imposes significant economic burden on patients and their societies. This study intends to assess the impact of the treatment with ketogenic diet (KD) on reducing seizure-related emergency room visits and hospitalizations in children with refractory epilepsy. Methods. This is a retrospective review of children treated with the KD in one tertiary center. We compared a 12 months' period prior to KD with 12 months after the diet was started in regard to the number of emergency department (ED) visits, hospitalizations, and hospital days as well as their associated charges. Results. 37 patients (57% males) were included. Their ages at time of KD initiation were (4.0 ± 2.78) years. Twelve months after the KD initiation, the total number of ED visits was reduced by 36% with a significant decrease of associated charges (p = 0.038). The number of hospital admissions was reduced by 40% and the number of hospital days was reduced by 39%. The cumulative charges showed net cost savings after 9 months when compared to the prediet baseline. Conclusion. In children with refractory epilepsy, treatment with the ketogenic diet reduces the number of ED visits and hospitalizations and their corresponding costs.

Journal Title

Epilepsy Res Treat

Volume

2016

First Page

5873208

Last Page

5873208

MeSH Keywords

Epilepsy; Diet, Ketogenic; Emergency Service, Hospital; Hospitalization; Utilization Review; Hospitals, Pediatric

Keywords

Children; Seizures; Children's Hospitals; Keto Diet

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