EPHB4 Mutation Suppresses PROX1 Expression and Disrupts Lymphatic Development in Neonatal Hydrops.

Creator(s)

Gangaram Akangire, Children's Mercy HospitalFollow
Heather Menden, Children's Mercy HospitalFollow
Sheng Xia, Children's Mercy HospitalFollow
Isabelle Thiffault, Children's Mercy HospitalFollow
Atif Ahmed, Children's Mercy Hospital
Venkatesh Sampath, Children's Mercy HospitalFollow

Document Type

Article

Publication Date

3-1-2022

Identifier

DOI: 10.1542/peds.2021-053294

Abstract

This case report highlights the importance of screening for mutations in EPHB4 and other genes that regulate lymphatic development in infants with the nonimmune hydrops fetalis.

Journal Title

Pediatrics

Volume

149

Issue

3

Recommended Citation

Akangire G, Menden H, Xia S, Thiffault I, Ahmed A, Sampath V. EPHB4 Mutation Suppresses PROX1 Expression and Disrupts Lymphatic Development in Neonatal Hydrops. Pediatrics. 2022;149(3):e2021053294. doi:10.1542/peds.2021-053294