Title

Symptom Profiles of Adolescents and Young Adults in Active Cancer Treatment by Diagnostic Groups.

Document Type

Article

Publication Date

7-2022

Identifier

DOI: 10.1097/NCC.0000000000001047; PMCID: PMC9207147

Abstract

BACKGROUND: The symptom experience of adolescents and young adults (AYAs) with cancer can differ based on the cancer and its treatments. A dearth of information exists on how symptoms differ by individual factors such as age and gender.

OBJECTIVES: The objectives were to describe symptoms in AYAs across 5 cancer diagnostic groups by the individual factors of age group, sex, race/ethnicity, and time since diagnosis; and then to describe symptoms based on these individual factors within diagnostic groups.

METHODS: This was a secondary analysis of baseline data pooled from 2 multisite studies on symptoms in AYAs with acute lymphoblastic leukemia, brain cancer, Hodgkin lymphoma, non-Hodgkin lymphoma, and sarcoma. Symptoms were assessed using the Computerized Symptom Capture Tool.

RESULTS: Data from 118 AYAs with cancer, aged 13 to 29 years, were analyzed. Eight of the most commonly reported symptoms were reported in at least 4 diagnostic groups. Across diagnostic groups, symptoms varied little based on individual factors. Within groups, certain symptoms differed in frequency by individual factors.

CONCLUSIONS: The lack of major differences in symptom prevalence based on individual factors across diagnostic groups supports a heterogeneous approach to symptom research with AYAs. The study identified individual factors within diagnostic groups worthy of further exploration.

IMPLICATIONS FOR PRACTICE: Providers can facilitate discussions with AYAs about symptoms by being aware of common symptoms that may occur in certain cancer diagnostic groups and based on individual factors. The significance of the individual symptom experience should not be underestimated, emphasizing the importance of person-centered symptom assessment.

Journal Title

Cancer nursing

Volume

45

Issue

4

First Page

306

Last Page

315

MeSH Keywords

Adolescent; Humans; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Symptom Assessment; Young Adult

Keywords

Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Symptom Assessment

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