Pulmonological issues.

Document Type

Article

Publication Date

12-2022

Identifier

DOI: 10.1016/j.cppeds.2022.101313

Abstract

Pediatric leukodystrophies are rare neurodegenerative diseases involving multiple systems. Each form has unique neurologic features but are characterized by encephalopathy with accompanying impairments evidenced in reflexes, muscle tone and movement control. Weakness of expiratory, inspiratory, and upper airway muscles may lead to impaired airway secretion clearance resulting in recurrent respiratory infections, dysphagia, sleep-disordered breathing, restrictive lung disease, and ultimately chronic respiratory insufficiency.

Journal Title

Current problems in pediatric and adolescent health care

Volume

52

Issue

12

First Page

101313

Last Page

101313

MeSH Keywords

Humans; Child; Sleep Apnea Syndromes

Keywords

Sleep Apnea Syndromes

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