Association of neighborhood segregation with 6-year incidence of metabolic syndrome in the Hispanic community health study/study of Latinos.

Creator(s)

Catherine M. Pichardo
Margaret S. Pichardo
Linda C. Gallo
Gregory A. Talavera
Earle C. Chambers
Lisa A P Sanchez-Johnsen
Amber Pirzada
Amanda L. Roy
Carmen Rodriguez
Sheila F. Castañeda
Ramon A. Durazo-Arvizu
Krista M. Perreira
Tanya P. Garcia
Matthew Allison
Jordan A. Carlson, Children's Mercy HospitalFollow
Martha L. Daviglus
Jesse J. Plascak

Document Type

Article

Publication Date

2-2023

Identifier

DOI: 10.1016/j.annepidem.2022.11.003

Abstract

PURPOSE: Examine the association between neighborhood segregation and 6-year incident metabolic syndrome (MetSyn) in the Hispanic Community Health Study/Study of Latinos.

METHODS: Prospective cohort of adults residing in Miami, Chicago, the Bronx, and San Diego. The analytic sample included 6,710 participants who did not have MetSyn at baseline. The evenness and exposure dimensions of neighborhood segregation, based on the Gini and Isolation indices, respectively, were categorized into quintiles (Q). Racialized economic concentration was measured with the Index of Concentration at the Extremes (continuously and Q).

RESULTS: Exposure, but not evenness, was associated with higher disease odds (Q1 (lower segregation) vs. Q4, OR = 1.53, 95% CI = 1.082.17; Q5, OR = 2.29, 95% CI = 1.493.52). Economic concentrationprivilege (continuous OR = 0.87, 95% CI = 0.770.98), racial concentrationracialized privilege (Q1 (greater concentration) vs. Q2 OR = 0.75, 95% CI = 0.541.04; Q3 OR = 0.68, 95% CI = 0.441.05; Q4 OR = 0.68, 95% CI = 0.451.01; Q5 OR = 0.64, 95% CI = 0.420.98)(continuous OR = 0.93, 95% CI = 0.821.04), and racialized economic concentrationprivilege (i.e., higher SES non-Hispanic White, continuous OR = 0.86, 95% CI = 0.760.98) were associated with lower disease odds.

CONCLUSION: Hispanics/Latino adults residing in neighborhoods with high segregation had higher risk of incident MetSyn compared to those residing in neighborhoods with low segregation. Research is needed to identify the mechanisms that link segregation to poor metabolic health.

Journal Title

Annals of epidemiology

Volume

78

First Page

1

Last Page

8

MeSH Keywords

Humans; Metabolic Syndrome; Prospective Studies; Public Health; Incidence; Hispanic or Latino; Residence Characteristics

Keywords

Hispanic/Latino; Metabolic syndrome; Neighborhood segregation; Racialized economic concentration

Recommended Citation

Pichardo CM, Pichardo MS, Gallo LC, et al. Association of neighborhood segregation with 6-year incidence of metabolic syndrome in the Hispanic community health study/study of Latinos. Ann Epidemiol. 2023;78:1-8. doi:10.1016/j.annepidem.2022.11.003