Recurrence Rates for Pediatric Benign Ovarian Neoplasms.
STUDY OBJECTIVE: To examine the recurrence rates of pediatric benign ovarian neoplasms METHODS: A retrospective review of females up to 21 years of age who underwent surgery for a benign ovarian neoplasm at 8 pediatric hospitals from January 2010 through December 2016 was conducted. Data include primary operation details, follow-up imaging, and reoperation details.
RESULTS: Four hundred and twenty-six females were included in our cohort, with a median age of 15 years at the time of the primary operation. Of the patients, 69% had a mature teratoma, 18% had a serous cystadenoma, and 8% had a mucinous cystadenoma. Two-thirds of patients underwent ovarian-sparing surgery. There were 11 pathologically confirmed recurrences (2.6%) at a median follow-up of 12.8 months. The pathologically confirmed recurrence was 10.5 per 100 person-months at 12 months (SE = 5.7) for mucinous cystadenomas and 0.4 months (SE = 0.4) for mature teratomas (P = .001). For half of the patients, the pathologically confirmed recurrences occurred by 12.8 months, and for 75%, they occurred by 23.3 months. There were no differences in reoperation or recurrence on the basis of initial procedure (ovary-sparing surgery vs oophorectomy).
CONCLUSION: We measured the pathologically confirmed recurrence rate for pediatric benign ovarian neoplasms in a large cohort. Oophorectomy was not protective against recurrence. Mucinous cystadenomas were at a greater risk of pathologically confirmed recurrence.
Journal of pediatric and adolescent gynecology
Child; Humans; Female; Adolescent; Cystadenoma, Mucinous; Ovarian Neoplasms; Teratoma; Dermoid Cyst; Retrospective Studies
Dermoid cyst; Mature cystic teratoma; Mature teratoma; Mucinous cystadenoma; Serous cystadenoma
Knaus ME, Onwuka AJ, Abouelseoud NM, et al. Recurrence Rates for Pediatric Benign Ovarian Neoplasms. J Pediatr Adolesc Gynecol. 2023;36(2):160-166. doi:10.1016/j.jpag.2022.11.006