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DOI: 10.1186/s12887-023-04259-9; PMCID: PMC10507904


BACKGROUND: Childhood obesity rates have continued to increase with the COVID-19 pandemic. However, data are limited on the impact of increasing obesity on associated comorbidities.

METHODS: We evaluated the progression of overweight- or obesity-associated comorbidities by investigating change in laboratory results pre-COVID-19 pandemic and post-COVID-19 pandemic onset in youth with overweight or obesity. We defined progression of comorbidities based on increase in category rather than absolute change in value.

RESULTS: HbA1c progression was seen in 19%, and LDL cholesterol progression was seen in 26%, as defined by categories. HbA1c progression and LDL cholesterol progression were significantly correlated. HbA1c and LDL cholesterol progression were significantly associated with older age and Hispanics, respectively.

CONCLUSION: The results indicate youths with overweight or obesity have experienced progression of comorbidities during the COVID-19 pandemic. This study emphasizes the importance of early detection of comorbidities among a high-risk pediatric population.

Journal Title

BMC pediatrics [electronic resource]





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MeSH Keywords

Child; Adolescent; Humans; Overweight; Cholesterol, LDL; Glycated Hemoglobin; Pandemics; Pediatric Obesity; COVID-19


COVID-19 pandemic; Comorbidities; Obesity; Prediabetes; Youth


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