Title

Priapism in the United States: the changing role of sickle cell disease.

Document Type

Article

Publication Date

4-1-2011

Identifier

DOI: 10.1016/j.amjsurg.2010.03.017

Abstract

BACKGROUND: Few patients with priapism require inpatient management unless they are refractory to intracavernosal therapy. Their risk factors and outcomes are poorly characterized.

METHODS: This is a retrospective analysis of the Nationwide Inpatient Sample (1998-2006). Priapism patients were identified and analyzed over time by age, race, sickle-cell disease diagnosis, drug abuse, and penile operations.

RESULTS: A total of 4,237 hospitalizations for priapism were identified (30% white, 61.1% black, and 6.3% Hispanics). There was an increasing incidence of priapism over time, concentrated in the middle-age group. There were 1,776 patients (41.9%) with diagnoses of sickle-cell disease, with decreasing proportions over time. Drug abuse was reported in 7.9%.

CONCLUSIONS: Inpatient diagnoses of priapism are increasing over time with relatively constant numbers of sickle-cell disease patients, suggesting rising nonhematologic causes of priapism. One theory is that increasing use of aggressive therapies for erectile dysfunction might play a role, especially when combined with drug abuse.

Journal Title

American journal of surgery

Volume

201

Issue

4

First Page

468

Last Page

474

MeSH Keywords

Adult; African Continental Ancestry Group; Age Distribution; Anemia; Sickle Cell; European Continental Ancestry Group; Hispanic Americans; Hospitalization; Humans; Male; Middle Aged; Penis; Priapism; Retrospective Studies; Risk Factors; Substance-Related Disorders; Time Factors; United States

Keywords

Sickle Cell Disease; Priapism; Risk; Drug Abuse

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