Priapism in the United States: the changing role of sickle cell disease.
BACKGROUND: Few patients with priapism require inpatient management unless they are refractory to intracavernosal therapy. Their risk factors and outcomes are poorly characterized.
METHODS: This is a retrospective analysis of the Nationwide Inpatient Sample (1998-2006). Priapism patients were identified and analyzed over time by age, race, sickle-cell disease diagnosis, drug abuse, and penile operations.
RESULTS: A total of 4,237 hospitalizations for priapism were identified (30% white, 61.1% black, and 6.3% Hispanics). There was an increasing incidence of priapism over time, concentrated in the middle-age group. There were 1,776 patients (41.9%) with diagnoses of sickle-cell disease, with decreasing proportions over time. Drug abuse was reported in 7.9%.
CONCLUSIONS: Inpatient diagnoses of priapism are increasing over time with relatively constant numbers of sickle-cell disease patients, suggesting rising nonhematologic causes of priapism. One theory is that increasing use of aggressive therapies for erectile dysfunction might play a role, especially when combined with drug abuse.
American journal of surgery
Adult; African Continental Ancestry Group; Age Distribution; Anemia; Sickle Cell; European Continental Ancestry Group; Hispanic Americans; Hospitalization; Humans; Male; Middle Aged; Penis; Priapism; Retrospective Studies; Risk Factors; Substance-Related Disorders; Time Factors; United States
Sickle Cell Disease; Priapism; Risk Factors; Drug Abuse
Chrouser, K. L., Ajiboye, O. B., Oyetunji, T. A., Chang, D. C. Priapism in the United States: the changing role of sickle cell disease. American journal of surgery 201, 468-474 (2011).