Giant ossifying malignant thymoma in a child.
We present the first reported case of an ossifying pediatric thymoma. Our patient was diagnosed with a massive thymoma replacing the whole of the left thoracic cavity. Percutaneous biopsy was attempted 3 times followed by an open incisional biopsy and adjuvant chemotherapy. Complete resection required a median sternotomy and a "trap door" thoracotomy after the tumor failed to respond to chemotherapy. Histology confirmed World Health Organization type B1 lymphocyte-rich thymoma, Masaoka stage I, with extensive osseous metaplasia.
Journal of pediatric surgery
Antineoplastic Combined Chemotherapy Protocols; Child; Female; Humans; Neoadjuvant Therapy; Ossification, Heterotopic; Thymoma; Thymus Neoplasms
Bikhchandani, Jai; Valusek, Patricia A.; Juang, David; O'Brien, James E.; Hetherington, Maxine; and St Peter, Shawn D., "Giant ossifying malignant thymoma in a child." (2010). Manuscripts, Articles, Book Chapters and Other Papers. 668.