Giant ossifying malignant thymoma in a child.
We present the first reported case of an ossifying pediatric thymoma. Our patient was diagnosed with a massive thymoma replacing the whole of the left thoracic cavity. Percutaneous biopsy was attempted 3 times followed by an open incisional biopsy and adjuvant chemotherapy. Complete resection required a median sternotomy and a "trap door" thoracotomy after the tumor failed to respond to chemotherapy. Histology confirmed World Health Organization type B1 lymphocyte-rich thymoma, Masaoka stage I, with extensive osseous metaplasia.
Journal of pediatric surgery
Antineoplastic Combined Chemotherapy Protocols; Child; Female; Humans; Neoadjuvant Therapy; Ossification, Heterotopic; Thymoma; Thymus Neoplasms
Chemotherapy; Neoadjuvant therapy; Cancer
Bikhchandani, J., Valusek, P. A., Juang, D., O'Brien, J. E., Hetherington, M., St Peter, S. D. Giant ossifying malignant thymoma in a child. Journal of pediatric surgery 45, 31-34 (2010).