Title

The diagnosis and management of empyema in children: a comprehensive review from the APSA Outcomes and Clinical Trials Committee.

Document Type

Article

Publication Date

11-1-2012

Identifier

DOI: 10.1016/j.jpedsurg.2012.07.047

Abstract

The aim of this study is to review the current evidence on the diagnosis and management of empyema. The American Pediatric Surgical Association Outcomes and Clinical Trials Committee compiled 8 questions to address. A comprehensive review was performed on each topic. Topics included the distinction between parapneumonic effusion and empyema, the optimal imaging modality in evaluating pleural space disease, when and how pleural fluid should be managed, the first treatment option and optimal timing in the management of empyema, the optimal chemical debridement agent for empyema, therapeutic options if chemical debridement fails, therapy for parenchymal abscess or necrotizing pneumonia and duration of antibiotic therapy after an intervention. The evidence was graded for each topic to provide grade of recommendation where appropriate.

Journal Title

Journal of pediatric surgery

Volume

47

Issue

11

First Page

2101

Last Page

2110

MeSH Keywords

Anti-Bacterial Agents; Child; Combined Modality Therapy; Debridement; Deoxyribonucleases; Drainage; Empyema, Pleural; Expectorants; Fibrinolytic Agents; Humans; Pleural Cavity; Pneumonia, Bacterial; Thoracic Surgery, Video-Assisted; Tomography, X-Ray Computed; Ultrasonography

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