Technical desiderata for the integration of genomic data into Electronic Health Records.

Creator(s)

Daniel R Masys
Gail P Jarvik
Neil F Abernethy
Nicholas R Anderson
George J Papanicolaou
Dina N Paltoo
Mark A HoffmanFollow
Isaac S Kohane
Howard P Levy

Document Type

Article

Publication Date

6-1-2012

Identifier

PMCID: PMC3328607, DOI: 10.1016/j.jbi.2011.12.005

Abstract

The era of "Personalized Medicine," guided by individual molecular variation in DNA, RNA, expressed proteins and other forms of high volume molecular data brings new requirements and challenges to the design and implementation of Electronic Health Records (EHRs). In this article we describe the characteristics of biomolecular data that differentiate it from other classes of data commonly found in EHRs, enumerate a set of technical desiderata for its management in healthcare settings, and offer a candidate technical approach to its compact and efficient representation in operational systems.

Journal Title

Journal of biomedical informatics

Volume

45

Issue

3

First Page

419

Last Page

422

MeSH Keywords

Databases; Factual; Delivery of Health Care; Electronic Health Records; Genomics; Humans; Precision Medicine

Keywords

Electronic medical record; Electronic health records; Genome

Comments

Grant support

• RC2 GM092618/GM/NIGMS NIH HHS/United States

• RC2 GM092618-01/GM/NIGMS NIH HHS/United States

• U54 LM008748/LM/NLM NIH HHS/United States

• 5RC2GM092618-02/GM/NIGMS NIH HHS/United States

http://www.sciencedirect.com/science/article/pii/S153204641100219X

Recommended Citation

Masys, D., Jarvik, G., Abernethy, N., Anderson, N., Papanicolaou, G., Paltoo, D., Hoffman, M., Kohane, I., Levy, H. Technical desiderata for the integration of genomic data into Electronic Health Records. Journal of biomedical informatics 45, 419-422 (2012).