Langerhans Cell Histiocytosis of the Pediatric Thoracic Spine with Development of Neurological Compromise: A Case Report.
Document Type
Article
Publication Date
7-2019
Identifier
DOI: 10.2106/JBJS.CC.18.00159
Abstract
CASE: This report describes a 7-year-old girl with Langerhans cell histiocytosis (LCH) of the thoracic spine who developed neurological deterioration during nonsurgical management. She was treated with decompression and instrumented fusion followed by chemotherapy, recovered completely after surgery, and was doing well at 6-year follow-up.
CONCLUSIONS: The best treatment of LCH of the spine is not clear, but in the setting of neurologic compromise after failing conservative management, surgical decompression with adjuvant chemotherapy should be considered.
Journal Title
JBJS Case Connect
Volume
9
Issue
3
First Page
0159
Last Page
0159
MeSH Keywords
Chemotherapy, Adjuvant; Child; Decompression, Surgical; Female; Histiocytosis, Langerhans-Cell; Humans; Spinal Diseases; Spinal Fusion; Thoracic Vertebrae
Keywords
Chemotherapy, Adjuvant; Surgical; Langerhans-Cell Histiocytosis; Spinal Diseases; Spinal Fusion; Thoracic Vertebrae
Recommended Citation
Burkes JC, Anderson JT. Langerhans Cell Histiocytosis of the Pediatric Thoracic Spine with Development of Neurological Compromise: A Case Report. JBJS Case Connect. 2019;9(3):e0159. doi:10.2106/JBJS.CC.18.00159