Second Reported Case of Pediatric Bladder Alveolar Soft Part Sarcoma as Secondary Malignancy After Prior Cytotoxic Chemotherapy.

Creator(s)

Justin Penticuff, Children's Mercy Hospital
Sarah McDermott, Children's Mercy Hospital
Alonso Carrasco, Children's Mercy HospitalFollow
Paul R. Bowlin, Children's Mercy HospitalFollow
Karen Lewing, Children's Mercy HospitalFollow
Joel F Koenig, Children's Mercy HospitalFollow

Document Type

Article

Publication Date

8-2019

Identifier

DOI: 10.1016/j.urology.2019.04.002

Abstract

Alveolar soft part sarcoma (ASPS) is a rare malignancy with high rates of metastasis at presentation, defined by an unclear cellular origin and a unique unbalanced ASPSCR1-TFE3 translocation (der(17)t(X:17)(p11:q25)).1 ASPS is insensitive to chemotherapy and has been reported to involve the bladder only twice in the pediatric literature; once as a primary malignancy,2 and once as a secondary malignancy after cytotoxic chemotherapy.3 Herein, we report the third case of pediatric bladder ASPS in a female patient who received cytotoxic chemotherapy for low-risk neuroblastoma. This would represent the second case of pediatric bladder ASPS as a secondary malignancy after prior chemotherapy.

Journal Title

Urology

Volume

130

First Page

148

Last Page

150

MeSH Keywords

Antineoplastic Agents; Female; Humans; Male; Neoplasms, Second Primary; Neuroblastoma; Sarcoma, Alveolar Soft Part; Urinary Bladder Neoplasms

Keywords

Antineoplastic Agents; Neoplasms, Second Primary; Neuroblastoma; Sarcoma, Alveolar Soft Part; Urinary Bladder Neoplasms

Recommended Citation

Penticuff J, McDermott S, Carrasco A, Bowlin P, Lewing K, Koenig JF. Second Reported Case of Pediatric Bladder Alveolar Soft Part Sarcoma as Secondary Malignancy After Prior Cytotoxic Chemotherapy. Urology. 2019;130:148-150. doi:10.1016/j.urology.2019.04.002