Title

Enterovirus D68–associated acute respiratory illness — new vaccine surveillance network, United States, July–October, 2017 and 2018

Creator(s)

Stephanie A. Kujawski, Centers for Disease Control and Prevention
Claire M. Midgley, National Center for Immunization and Respiratory Diseases
Brian Rha, National Center for Immunization and Respiratory Diseases
Joana Y. Lively, National Center for Immunization and Respiratory Diseases
W. Allan Nix, National Center for Immunization and Respiratory Diseases
Aaron T. Curns, National Center for Immunization and Respiratory Diseases
Daniel C. Payne, National Center for Immunization and Respiratory Diseases
Janet A. Englund, Seattle Children's Hospital
Julie A. Boom, Texas Children's Hospital Houston
John V. Williams, University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh
Geoffrey A. Weinberg, University of Rochester School of Medicine and Dentistry
Mary A. Staat, University of Cincinnati College of Medicine
Rangaraj Selvarangan, Children's Mercy HospitalFollow
Natasha B. Halasa, Vanderbilt University Medical Center
Eileen J. Klein, Seattle Children's Hospital
Leila C. Sahni, Texas Children's Hospital Houston
Marian G. Michaels, University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh
Lynne Shelley, University of Rochester School of Medicine and Dentistry
Monica McNeal, University of Cincinnati College of Medicine
Christopher J. Harrison, Children's Mercy HospitalFollow
Laura S. Stewart, Vanderbilt University Medical Center
Adriana S. Lopez, National Center for Immunization and Respiratory Diseases
Janell A. Routh, National Center for Immunization and Respiratory Diseases
Manisha Patel, National Center for Immunization and Respiratory Diseases
M. Steven Oberste, National Center for Immunization and Respiratory Diseases
John T. Watson, National Center for Immunization and Respiratory Diseases
Susan I. Gerber, National Center for Immunization and Respiratory Diseases

Document Type

Article

Publication Date

3-29-2019

Identifier

DOI: 10.15585/mmwr.mm6812a1; PMCID: PMC6448985

Abstract

In the fall of 2014, an outbreak of enterovirus D68 (EV-D68)-associated acute respiratory illness (ARI) occurred in the United States (1,2); before 2014, EV-D68 was rarely reported to CDC (2,3). In the United States, reported EV-D68 detections typically peak during late summer and early fall (3). EV-D68 epidemiology is not fully understood because testing in clinical settings seldom has been available and detections are not notifiable to CDC. To better understand EV-D68 epidemiology, CDC recently established active, prospective EV-D68 surveillance among pediatric patients at seven U.S. medical centers through the New Vaccine Surveillance Network (NVSN) (4). This report details a preliminary characterization of EV-D68 testing and detections among emergency department (ED) and hospitalized patients with ARI at all NVSN sites during July 1-October 31, 2017, and the same period in 2018. Among patients with ARI who were tested, EV-D68 was detected in two patients (0.8%) in 2017 and 358 (13.9%) in 2018. Continued active, prospective surveillance of EV-D68-associated ARI is needed to better understand EV-D68 epidemiology in the United States.

Journal Title

Morbidity and Mortality Weekly Report

Volume

68

Issue

12

First Page

277

Last Page

280

Comments

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