Colostomy in children on chronic peritoneal dialysis.

Creator(s)

Eugene Y H Chan
Dagmara Borzych-Duzalka
Caner Alparslan
Elizabeth Harvey
Reyner Loza Munarriz
Dariusz Runowski
Enrico Vidal
Paula A. Coccia
Augustina Jankauskiene
Iliana Principi
Erkin Serdaroglu
Maria Szczepanska
Yincent Tse
Aida Vazquez
Donald J. Weaver
Franz Schaefer
Bradley A. Warady, Children's Mercy HospitalFollow
International Pediatric Peritoneal Dialysis Network

Document Type

Article

Publication Date

1-2020

Identifier

DOI: 10.1007/s00467-019-04372-x

Abstract

BACKGROUND: This study aimed to evaluate outcome of children on chronic peritoneal dialysis (PD) with a concurrent colostomy.

METHODS: Patients were identified through the International Pediatric Peritoneal Dialysis Network (IPPN) registry. Matched controls were randomly selected from the registry. Data were collected through the IPPN database and a survey disseminated to all participating sites.

RESULTS: Fifteen centers reported 20 children who received chronic PD with a co-existing colostomy. The most common cause of end stage kidney disease was congenital anomalies of the kidney and urinary tract (n = 16, 80%). The main reason for colostomy placement was anorectal malformation (n = 13, 65%). The median age at colostomy creation and PD catheter (PDC) insertion were 0.1 (IQR, 0-2.2) and 2.8 (IQR 0.2-18.8) months, respectively. The colostomies and PDCs were present together for a median 18 (IQR, 4.9-35.8) months. The median age at PDC placement in 46 controls was 3.4 (IQR, 0.2-7.4) months of age. Fourteen patients (70%) developed 39 episodes of peritonitis. The annualized peritonitis rate was significantly higher in the colostomy group (1.13 vs. 0.70 episodes per patient year; p = 0.02). Predominant causative microorganisms were Staphylococcus aureus (15%) and Pseudomonas aeruginosa (13%). There were 12 exit site infection (ESI) episodes reported exclusively in colostomy patients. Seven colostomy children (35%) died during their course of PD, in two cases due to peritonitis.

CONCLUSION: Although feasible in children with a colostomy, chronic PD is associated with an increased risk of peritonitis and mortality. Continued efforts to reduce infection risk for this complex patient population are essential.

Journal Title

Pediatric nephrology (Berlin, Germany)

Volume

35

Issue

1

First Page

119

Last Page

126

Keywords

Children; Colostomy; Exit site infection; Ostomy; Peritoneal dialysis; Peritonitis

Recommended Citation

Chan EYH, Borzych-Duzalka D, Alparslan C, et al. Colostomy in children on chronic peritoneal dialysis. Pediatr Nephrol. 2020;35(1):119-126. doi:10.1007/s00467-019-04372-x