The Rare Association of Cleft Lip and/or Palate and Wilms Tumor.

Creator(s)

Elizabeth Theng
Meghan Tracy, Children's Mercy HospitalFollow
Susan Starling Hughes, Children's Mercy HospitalFollow
Alison Kaye, Children's Mercy HospitalFollow

Document Type

Article

Publication Date

9-2019

Identifier

DOI: 10.1177/1055665618824440

Abstract

There is currently no recognized connection between the occurrence of cleft lip and/or palate (CL/P) and Wilms tumor (WT). A retrospective review of cleft team records (2001-2015) revealed 3 cases of children, all male, with concomitant diagnoses of CL/P and WT treated at our institution. These patients presented as infants for care of their CL/P, all with additional congenital anomalies, developmental delays, and growth delays. Between the ages of 1 and 4 years, each was diagnosed with WT, which was treated with chemotherapy and partial nephrectomy, +/- radiation, leading to full remission in all cases.

Journal Title

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

Volume

56

Issue

8

First Page

1096

Last Page

1106

MeSH Keywords

Child; Child, Preschool; Cleft Lip; Cleft Palate; Humans; Infant; Kidney Neoplasms; Male; Retrospective Studies; Wilms Tumor

Keywords

Wilms tumor; cleft lip and palate

Recommended Citation

Theng E, Tracy M, Hughes SS, Kaye A. The Rare Association of Cleft Lip and/or Palate and Wilms Tumor. Cleft Palate Craniofac J. 2019;56(8):1096-1106. doi:10.1177/1055665618824440