Parental health literacy and progression of chronic kidney disease in children.

Document Type

Article

Publication Date

10-2018

Identifier

DOI: 10.1007/s00467-018-3962-y; PMCID: PMC6129202

Abstract

Background: Limited health literacy has been associated with adverse outcomes in children. We evaluated this association in the setting of chronic kidney disease (CKD).

Methods: We assessed the parental health literacy of 367 children enrolled in the Chronic Kidney Disease in Children (CKiD) Study, using the Short Test of Functional Health Literacy (STOFHLA). We evaluated the association between parental health literacy and CKD progression, defined as time to the composite event of renal replacement therapy (RRT, dialysis, or kidney transplant) or 50% decline in estimated glomerular filtration rate (eGFR).

Results: Median CKiD participant age was 9.5 years, 63% were male, and 59% non-Hispanic white. Median eGFR at baseline was 63 ml/min/1.73 m2, and median urine protein-to-creatinine ratio was 0.22. The median STOFHLA score was 98. Over a median follow-up of 3.7 years, the overall CKD progression rate was 2.8 per 100 person-years. After adjustment for demographic and clinical factors, the relative time to CKD progression was 28% longer per 1 SD increase in STOFHLA score (relative time, 95% CI, 1.28, 1.06-1.53).

Conclusions: In this cohort of children with CKD, higher parental health literacy was associated with a nearly 30% longer time to the composite CKD progression outcome.

Journal Title

Pediatric nephrology (Berlin, Germany)

Volume

33

Issue

10

First Page

1759

Last Page

1764

MeSH Keywords

Adolescent; Adult; Child; Child, Preschool; Disease Progression; Female; Glomerular Filtration Rate; Health Literacy; Humans; Male; Parents; Renal Insufficiency, Chronic; Renal Replacement Therapy; Reproducibility of Results; Risk Factors; Severity of Illness Index; Socioeconomic Factors; Time Factors

Keywords

Children; Chronic kidney disease; Health literacy

Link to Full Text
Library Record

Share

COinS