Obesity-related asthma in children: A role for vitamin D.

Document Type

Article

Publication Date

2-2021

Identifier

DOI: 10.1002/ppul.25053

Abstract

Excess adipose tissue predisposes to an enhanced inflammatory state and can contribute to the pathogenesis and severity of asthma. Vitamin D has anti-inflammatory properties and low-serum levels are seen in children with asthma and in children with obesity. Here we review the intersection of asthma, obesity, and hypovitaminosis D in children. Supplementation with vitamin D has been proposed as a simple, safe, and inexpensive adjunctive therapy in a number of disease states. However, little research has examined the pharmacokinetics of vitamin D and its therapeutic potential in children who suffer from obesity-related asthma.

Journal Title

Pediatric pulmonology

Volume

56

Issue

2

First Page

354

Last Page

361

Keywords

asthma; children; inflammation; obesity; pediatric; vitamin D

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